1996-2008:美國國家衛(wèi)生研究院基因調(diào)控與發(fā)育實驗室? 研究員
1992-1996:? 華盛頓卡內(nèi)基研究所胚胎系D. Koshland博士實驗室? 博士后
1989-1991:俄羅斯科學(xué)院細胞研究所V. Larionov博士有絲分裂基因?qū)W實驗室研究生
1989:BioTechnika Ltd. 和 匈牙利生物研究中心? 訪問學(xué)者
1987-1988:俄羅斯科學(xué)院細胞研究所染色體穩(wěn)定與細胞工程實驗室? 研究實習(xí)員
1985-1986:圣彼得堡流感研究所生物技術(shù)研究中心 基因工程系? 實習(xí)和技術(shù)員
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2009-至今:攻讀馬里蘭州大學(xué)生物技術(shù)和生物信息學(xué)碩士 (非全日制,2012年畢業(yè))
2010-2011:美國癌癥研究所癌癥研究中心“臨床腫瘤學(xué)轉(zhuǎn)化研究”繼續(xù)教育課程(兩個學(xué)期)
2008-2009:美國衛(wèi)生研究所非學(xué)位課程:逆轉(zhuǎn)錄酶病毒,動物實驗操作程序,芯片技術(shù),高通量篩選數(shù)據(jù)分析,Unix原理,高級SAS, 平行計算及其他。
1995: Cold Spring Harbor 實驗室課程:蛋白純化與特征
1987-1991:俄羅斯科學(xué)院細胞研究所博士學(xué)位
?????????? 導(dǎo)師:Dr. V. Larionov.
????? ?????論文題目:控制染色體在有絲分裂中分布的相關(guān)基因研究
1979-1984: 圣彼得堡大學(xué)生物與遺傳學(xué)學(xué)士學(xué)位(優(yōu)秀)
主修:生物學(xué)和遺傳學(xué), 兼修:生物教學(xué)
1999:提名為美國衛(wèi)生研究院院長發(fā)言人之一
2001:霍德休斯醫(yī)學(xué)研究所導(dǎo)師資格
2006:為美國政府服務(wù)十年榮譽證書
職業(yè)協(xié)會會員資格:????????????????????????????
美國遺傳協(xié)會
美國生物細胞協(xié)會
美國科學(xué)促進會
參加的項目評審小組:?????????????????????????????????????????????
2005: 美國國家衛(wèi)生研究院細胞核動態(tài)和運輸特別研究小組
美國國家科學(xué)基金會
瑞士國家科學(xué)基金會
奧地利Fonds zur Forderung der Wisscenschaftlishen Forsung,
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意大利癌癥研究協(xié)會
英國國際癌癥研究協(xié)會
英國威康信托基金會
新加坡科學(xué)技術(shù)研究會
新加坡生物醫(yī)藥研究理事會
新西蘭皇家馬斯登基金會
參加的演講與學(xué)術(shù)報告????????????????????????????????????????????????
應(yīng)邀在美國國內(nèi)及國際會議和學(xué)術(shù)報告會上多次發(fā)表演講:
1994年 美國舊金山細胞生物學(xué)學(xué)會年度會議
1995年 新墨西哥州陶斯細胞周期國際會議
1997年 新墨西哥州圣達菲細胞核組織和功能會議
1999年 美國國家衛(wèi)生研究院學(xué)術(shù)報告演講人
2000年 費城美國人類遺傳學(xué)會第50屆會議
2000年 美國實驗生物學(xué)聯(lián)合會舉辦的關(guān)于染色體組織和復(fù)制會議
2002年 馬爾堡大學(xué)學(xué)術(shù)報告會
2002年 英國醫(yī)學(xué)研究理事會學(xué)術(shù)報告會
2002年 法國巴斯德研究院學(xué)術(shù)報告會
2005年 日本岡崎機制擴大國際會議
2005年 荷蘭奈梅亨分子科學(xué)中心學(xué)術(shù)報告會
2005年 美國吉斯通DNA復(fù)制會議
2007年 日本靜岡市細胞周期國際會議
2007年 日本東京科技學(xué)院學(xué)術(shù)報告會
2008年 西班牙巴塞羅那癌癥預(yù)測和個體化醫(yī)學(xué)中心國際研討會
2009年 日本沖繩理工學(xué)院學(xué)術(shù)報告會
2010年 西班牙發(fā)展生物學(xué)安達盧西亞中心學(xué)術(shù)報告會
?* E. Pugacheva, T. Suzuki, S. Pack, N. Kosaka-Suzuki, J. Yoon, A. Vostrov, E. Barsov, A.Strunnikov, H. Morse III, D. Loukinov, V. Lobanenkov. (2010) The structural complexity of the human BORIS gene in gametogenesis and cancer. PLoS ONE 5:e13872
* A. Samoshkin, A. Arnaoutov, L.E.T. Jansen, I. Ouispenski, L. Dye, T. Karpova, J. McNally, M.Dasso, Don W. Cleveland and A. Strunnikov. (2009) Human condensin function is essential for centromeric chromatin assembly and sister kinetochore orientation. PLoS ONE 4:e6831
* S. Dulev, C. de Renty, R. Mehta, I. Minkov, E. Schwob and A. Strunnikov. (2009) Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants. PNAS 106: 14466-14471
* Y. Takahashi, S. Dulev, X. Liu, N. Hiller, X. Zhao and A. Strunnikov (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genetics 4:e1000215
* S. Dulev, L. Aragon, and A Strunnikov (2008) Unreplicated DNA in mitosis precludes condensin binding and chromosome condensation in S. cerevisae. Frontiers in Biosciences 13:5838-5846
* Y. Takahashi and A. Strunnikov (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117:189-198
* B.D. Wang and A. Strunnikov (2008) Transcriptional homogenization of rDNA repeats in the episome-based nucleolus induces genome-wide changes in the chromosomal distribution of condensin. Plasmid 59:45-53
* V. Yong-Gonzalez, B.D. Wang, P. Butylin, I. Ouspenski and A. Strunnikov (2007) Condensin function at centromere chromatin facilitates proper kinetochore tension and ensures correct mitotic segregation of sister chromatids. Genes to Cells 12:1075-1090
* B. D. Wang, P. Butylin and A. Strunnikov (2006) Condensin function in mitotic nucleolar segregation is regulated by rDNA transcription. Cell Cycle 5:2260-2267
* Y. Takahashi, V. Yong-Gonzalez, Y. Kikuchi and A. Strunnikov (2006) The SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by their role in sumoylation of topoisomerase II. Genetics 172:783-794
* B. Quimby, V. Yong-Gonzalez, T. Anan, A. Strunnikov and M. Dasso (2006) The
promyelocytic leukemia protein (PML) stimulates Sumo conjugation in yeast. Oncogene 25:2999-3005
* B.D. Wang, D. Eyre, M. Basrai, M. Lichten and A. Strunnikov (2005) Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome. Molecular and Cellular Biology 25: 7216-7225
* B. D. Wang, V. Yong-Gonzalez and A. Strunnikov. (2004) Cdc14p/FEAR pathway controls segregation of nucleolus in S. cerevisiae by facilitating condensin targeting to rDNA chromatin in anaphase. Cell Cycle 3:960-967
* A. Kagansky, L. Freeman, D. Lukyanov, and A. Strunnikov. (2004) Histone-tail independent chromatin-binding activity of recombinant cohesin holocomplex. Journal of Biological Chemistry 279:3382-3388
* J. Mascarenhas, J. Soppa , A. Strunnikov and P. L. Graumann (2002) Cell cycle dependent localization of two novel prokaryotic chromosome segregation and condensation proteins in Bacillus subtilis that interact with SMC protein. EMBO Journal. 21:3108-3128
* A. Strunnikov, L. Aravind and E. V. Koonin (2001) Saccharomyces cerevisiae SMT4 encodes an evolutionarily conserved protease with a role in chromosome condensation regulation. Genetics.158: 95- 107
* L. Aragon-Alcaide and A. Strunnikov (2000) Functional dissection of in-vivo interchromosome association in S. cerevisiae. Nature Cell Biology 2: 812-818
* L. Freeman, L.Aragon-Alcaide and A. Strunnikov (2000) The condensin complex governs chromosome condensation and mitotic transmission of rDNA. Journal of Cell Biology 149: 811-824
* N. Darwiche, L. A. Freeman , and A. Strunnikov (1999) Characterization of the components of the putative mammalian sister chromatid cohesion complex. Gene. 233:39-47
* P. L. Graumann, R. Losick, A. V. Strunnikov (1998) Subcellular localization of Bacillus subtilis SMC, a protein involved in chromosome condensation and segregation. Journal of Bacteriology 180:5749-5755
* V. Guacci, D. Koshland, A.V. Strunnikov (1997) A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S.cerevisiae. Cell 91:47-57
A. Strunnikov, E. Hogan and D. Koshland (1995) SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation defines a subgroup within the SMCfamily. Genes and Development 9: 87-599
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A. Strunnikov, J. Kingsbury and D. Koshland (1995) CEP3 encodes a centromere protein of Saccharomyces cerevisiae. Journal of Cell Biology 128:749-760
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A. Strunnikov, V. Larionov and D. Koshland (1993) SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family. Journal of Cell Biology 123:1635-1648
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V. Guacci, A. Yamamoto, A. Strunnikov, J. Kingsbury, E. Hogan, P. Meluh and D. Koshland (1993) Structure and function of chromosomes in mitosis of budding yeast. In: Cold Spring Harbor Symposia on Quantitative Biology /DNA and Chromosomes. 58:677-685, Cold Spring Harbor, New York
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V. Larionov, N. Kouprina N., A. Strunnikov and A. Vlasov (1989) A direct selection procedure for isolating yeast mutants with an impaired segregation of artificial minichromosomes. Current Genetics 15:17-26
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V. Larionov, N. Kouprina, A. Strunnikov, A. Vlasov and V. Pirozhkov (1989) Direct selection procedure for isolation of yeast mutants with impaired segregation of chromosomes. Progress in Clinical and Biological Research, Vol. 138: Mechanisms of chromosome distribution and aneuploidy, 303-316; Alan R. Liss, Inc., New York
評論和圖書章節(jié)??????????????????????????????????????????????????????
* A. Strunnikov (2010) One-hit wonders of genomic instability. Cell Division 5: 15
* Y. Takahashi, Iwase M, A. Strunnikov, Y. Kikuchi (2008) Cytoplasmic sumoylation by PIAStype Siz1-SUMO ligase. Cell Cycle. 7:1738-1744
* A. Strunnikov (2006) SMC complexes in bacterial chromosome condensation and segregation. Plasmid 55:135-144
* A. Strunnikov. (2005) A case of selfish nucleolar segregation. Cell Cycle 4: 113-117
* A. Strunnikov. (2003) Condensin and biological role of chromosome condensation. Progress in Cell Cycle Research 5: 361-368
* P. Meluh and A. V. Strunnikov (2002) Beyond the ABC of CKC and SCC. Do centromeres orchestrate sister chromatid cohesion or vice versa? European Journal of Biochemistry. 269:2300–2314
* A. V. Strunnikov, R. Jessberger (1999) SMC Proteins: Conserved molecular properties for multiple biological functions. European Journal of Biochemistry. 263:6-13
* A. V. Strunnikov (1998) SMC proteins and chromosome structure. Trends in Cell Biology. 8:454-459
* D. Koshland and, A. Strunnikov (1996) Mitotic chromosome condensation. Annual Reviews of Cell and Developmental Biology 12:305-333
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